It’s also simple with hard disk drives. Unfasten the single screw the HDD cage is secured with and pull it out:

The cage is equipped with rubber vibration-suppressing spacers:

The HDD is fastened with special screws:

There’s a groove at the side of the case to tuck away the power cable neatly:

The drive is inserted into the cage and fastened with screws through the rubber spacers:

And then the whole arrangement is pushed back into the system case: