Duke Nukem Forever
In terms of performance Duke Nukem Forever is an easy one for contemporary graphics cards. Except Radeon HD 6970, every tested graphics setup runs at speeds beyond 60+ fps. Disabling or enabling FSAA does not make a big impact on overall performance, so you may also consider playing around with image quality settings to speed up even more.
This is a new game on an old engine. Yes, the textures are a bit old and overall gameplay is over a decade old, but who cares? This game is yet another wonderful example of how an extra pair of monitors can change the whole experience. The DNF world is filled with details and objects, at the same time there is no need to really aim (since you are Duke and even if you miss your target, you still kick ass).
The advantage of having additional monitors is especially obvious in big arena fights and boss encounters. Dodging bullets becomes piece of cake and it is virtually impossible for a monster to jump you from behind. Multiplayer fight also becomes quite different and it is probably fair to say that triple-monitor configurations are equivalent to cheating in DNF player vs. player fights. But hey, winning is winning, right?
Rusty post-nuclear tunnels of Moscow metro system are just as hard on the player as the game is hard on the hardware. Multiplying the rendered space only contributes to the whole GPU stress, so it is quite natural that none of the testing participants were powerful enough to ensure comfortable gaming experience. Dreadnoughts like Radeon HD 6990 and GeForce GTX 590 can only squeeze out around 30 fps in this first-person shooter. The situation with GeForce GTX 560 Ti SLI is pretty interesting, though. At first it starts strong and even manages to top the competition. However, later on this SLI configuration fails to digest the 5760x1080 resolution.
The overall feel from playing Metro 2033 game on a triple-display system is pretty much the same as from Aliens vs. Predator. The majority of levels are narrow and dark corridors, which do not leave many details for your peripheral vision. On top of that, you are constantly out of ammo, so you trying to aim for the head in order to save a bullet or two. Sniping requires blinders over widescreen display setups.
S.T.A.L.K.E.R.: Call of Pripyat
The only thing you need to know about graphics configuring in S.T.A.L.K.E.R.: Call of Pripyat is that you have to disable FSAA, if you plan on playing this inspiring game in a 5760x1080 resolution. In terms of performance Nvidia-powered solutions would be a bit better pick here. Radeon HD 6970 with a single GPU is unable to deal with the workload, so be prepared to invest heavily in your Zone gaming station.
Even though this particular title is one of the best examples of just how important the atmosphere in the game is, S.T.A.L.K.E.R.: Call of Pripyat is not the best illustration of triple-monitor configuration advantages. For some reason, you really don't pay that much attention to your surroundings and aiming straight ahead is probably something you do most while exploring the Zone.